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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498867Generated: October 31, 2026

Trifluoroacetic acid → HCID 69487063, compound

https://huagongshe.com/reaction/498867

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589508HCID 86589508—
SolventDichloromethaneHCID 6344—
ProductHCID 69487063HCID 69487063—

Reaction Steps

The title compound was prepared from [2-{3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-(isopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example M307) (0.43 g, 0.72 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light brown solid (310 mg, 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-5752adff64bd441e9a0d968d5f2f78ec
Source noteuspto-grants-2005_09