3-(3-Methylphenoxy)propan-1-ol → 3-(3-methylphenoxy)propanoic acid

HRID 499016Notes

Reaction equation

HRID 499016 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][CH2:7][CH2:8][OH:9].CC(C)=[O:15].OS(O)(=O)=O.O=[Cr](=O)=O>CC(C)=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][CH2:7][C:8]([OH:15])=[O:9]

Participants

4

Reactant 2

HCID 122931893-(3-Methylphenoxy)propan-1-olHCID 131709961Jones' reagent

Product 1

HCID 7523133-(3-methylphenoxy)propanoic acid

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

This compound was prepared in a manner analogous to that of Step C of Example 2, by the reaction of 2.0 grams (0.012 mole) of 3-(3-methylphenoxy)propan-1-ol and 10 mL of Jones Reagent in 30 mL of acetone. The yield of subject compound was 1.5 grams. The NMR spectrum was consistent with the proposed structure.

Workup

  1. customThis compound was prepared in a manner analogous to that of Step C of Example 2

Sources & evidence

ORD record
ord-82e4471f90604136b4bf066cc6d1906c
Source dataset
uspto-grants-2010_08
Patent number
US07767667B2

Reaction notes

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