HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59420727, compound → HCID 59420747, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59420727 | HCID 59420727 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 59420747 | HCID 59420747 | — |
Reaction Steps
2-(2,2,2-trifluoroethyl)-5-((triisopropylsilyl)sulfanyl)isoindolin-1-one was dissolved in a solution of hydrochloric acid in methanol (2 ml) and tetrahydrofuran (2 ml) and stirred at room temperature for 2 hours or until disappearance of starting material. Reaction mixture concentrated to give desired material (quant yield). ES+ 248
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767672B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-e3cbe73007e74462ad4fc2217bcd68b0 |
| Source note | uspto-grants-2010_08 |