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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 499099Generated: October 30, 2026

HCID 59420727, compound → HCID 59420747, compound

https://huagongshe.com/reaction/499099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59420727HCID 59420727—
SolventHydrochloric AcidHCID 313—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 59420747HCID 59420747—

Reaction Steps

2-(2,2,2-trifluoroethyl)-5-((triisopropylsilyl)sulfanyl)isoindolin-1-one was dissolved in a solution of hydrochloric acid in methanol (2 ml) and tetrahydrofuran (2 ml) and stirred at room temperature for 2 hours or until disappearance of starting material. Reaction mixture concentrated to give desired material (quant yield). ES+ 248

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07767672B2
Source datasetuspto-grants-2010_08
ORD IDord-e3cbe73007e74462ad4fc2217bcd68b0
Source noteuspto-grants-2010_08