Water → HCID 68453456, compound

Participants

Reaction Conditions

Reaction Steps

5 g of the compound obtained in step 3.2 dissolved in 45 ml of THF are added to a solution of 1 g of LiA1H4 in 45 ml of THF cooled to 0° C. The medium is stirred at AT for two hours and then cooled to 0° C. 0.96 ml of water and then 3 ml of 5M NaOH are added, the medium is then filtered, and the solid is rinsed with ether. The filtrate is evaporated, taken up in ether, and washed twice with a saturated NaHCO3 solution and then with a saturated NaCl solution. After drying over MgSO4 and evaporation, 3.5 g of the desired compound are recovered.

Provenance & Evidence