HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49926Generated: October 25, 2026
Hydrochloric Acid → 6-Quinolinecarboxylic acid, ethyl ester
https://huagongshe.com/reaction/49926
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 6-Quinolinecarboxylic acid | HCID 82571 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Quinolinecarboxylic acid, ethyl ester | HCID 94670 | — |
Reaction Steps
4.9 g of quinoline-6-carboxylic acid was stirred in 80 ml of ethanol. 40 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture. After stirring at 70° C. overnight, the solvent was evaporated and the residue was treated with ethyl acetate as the extracting solvent by an ordinary method to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06710056B2 |
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| Source dataset | uspto-grants-2004_03 |
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| ORD ID | ord-39bdd5917a824cf489af4d15fa464529 |
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| Source note | uspto-grants-2004_03 |
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