HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59750154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | Ethyl 2-cyanopyridine-4-carboxylate | HCID 13415157 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 59750154 | HCID 59750154 | 71.9% |
Reaction Steps
A mixture of methyl thiosalicylate (3.0 g, 17.8 mmol), ethyl 2-cyanoisonicotinate (3.1 g, 17.8 mmol), triethylamine (5.0 ml, 35.8 mmol) and toluene (10 ml) was refluxed for 8 hrs as described in Example 1. The precipitated crystals were collected by filtration and recrystallized from diisopropylether-chlorobenzene to give the titled compound (4.0 g, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767665B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-4f783a43eb5440d480dffe46977eb149 |
| Source note | uspto-grants-2010_08 |