HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49931Generated: October 25, 2026
Hydrochloric Acid → Ethyl 5-nitrothiophene-2-carboxylate
https://huagongshe.com/reaction/49931
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 5-Nitro-2-thenoic acid | HCID 80591 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 5-nitrothiophene-2-carboxylate | HCID 304627 | — |
Reaction Steps
5 g of 5-nitrothiophene-2-carboxylic acid was stirred in 100 ml of ethanol. 20 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture, and they were stirred at 60° C. for 2 days. The solvent was evaporated to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06710056B2 |
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| Source dataset | uspto-grants-2004_03 |
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| ORD ID | ord-f84d5a426a894c01af94fb8ebc136096 |
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| Source note | uspto-grants-2004_03 |
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