HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59750374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | 2-(Morpholin-4-yl)pyridine-4-carbonitrile | HCID 14640856 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 59750374 | HCID 59750374 | 25% |
Reaction Steps
Methyl thiosalicylate (0.49 g, 2.9 mmol) and 2-morpholinylisonicotinonitrile (0.38 g, 2.0 mmol) were dissolved in toluene (2.0 ml), and triethylamine (0.48 ml, 3.4 mmol) was added thereto. The reaction mixture was refluxed for 14 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from ethanol. The obtained crystals were recrystallized from ethyl acetate again to give the titled compound (0.16 g, 25%) as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767665B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-601a6cb922f445d5b2117c77b2866319 |
| Source note | uspto-grants-2010_08 |