Triethylamine → 2-(4-Cyano-2-pyridyl)-4H-1,3-benzothiazine-4-one

Beteiligte Stoffe

Reaktionsschritte

A mixture of methyl thiosalicylate (0.65 g, 3.9 mmol), 2,4-dicyanopyridine (0.50 g, 3.9 mmol), triethylamine (0.81 ml, 5.8 mmol) and toluene (2.0 ml) was refluxed for 2.5 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from acetone-chloroform to give the titled compound (0.54 g, 53%).

Herkunft & Nachweise