HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → 1-Ethyl-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.1]heptane bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 1-Azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol | HCID 42625856 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Ethyl-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.1]heptane bromide | HCID 16041396 | 65.3% |
Reaction Steps
Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (31.3 mg, 0.112 mmol) and bromoethane (0.03 mL, 0.4 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (28.4 mg, 65%). EI-MS m/z 308 (M+) Rt (1.49 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767691B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-05355a08ca90485c8425cd247d76061f |
| Source note | uspto-grants-2010_08 |