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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 499660Generated: October 25, 2026

Ethyl Bromide → 1-Ethyl-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.1]heptane bromide

https://huagongshe.com/reaction/499660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl BromideHCID 6332—
Reactant1-Azabicyclo[2.2.1]hept-4-yl(diphenyl)methanolHCID 42625856—
SolventAcetonitrileHCID 6342—
Product1-Ethyl-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.1]heptane bromideHCID 1604139665.3%

Reaction Steps

Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (31.3 mg, 0.112 mmol) and bromoethane (0.03 mL, 0.4 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (28.4 mg, 65%). EI-MS m/z 308 (M+) Rt (1.49 min).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07767691B2
Source datasetuspto-grants-2010_08
ORD IDord-05355a08ca90485c8425cd247d76061f
Source noteuspto-grants-2010_08