(4-Bromobutoxy)benzene → 4-[Hydroxy(diphenyl)methyl]-1-[4-(phenyloxy)butyl]-1-azoniabicyclo[2.2.1]heptane bromide

Participants

Reaction Steps

Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (31.8 mg, 0.114 mmol) and 4-bromobutyl phenyl ether (44.3 mg, 0.193 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (38.7 mg, 67%). EI-MS m/z 428 (M+) Rt (1.98 min).

Provenance & Evidence