Benzyl 3-Bromopropyl Ether → 4-[Hydroxy(diphenyl)methyl]-1-{3-[(phenylmethyl)oxy]propyl}-1-azoniabicyclo[2.2.1]heptane bromide

Participants

Reaction Steps

Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (30.4 mg, 0.109 mmol) and 3-bromopropyl phenylmethyl ether (0.03 mL, 0.17 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (29.1 mg, 53%). EI-MS m/z 428 (M+) Rt (1.93 min).

Provenance & Evidence