((4-Bromobutoxy)methyl)benzene → 4-[Hydroxy(diphenyl)methyl]-1-{4-[(phenylmethyl)oxy]butyl}-1-azoniabicyclo[2.2.1]heptane bromide

Participants

Reaction Steps

Following the general procedure outlined in Example 1, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (33.1 mg, 0.118 mmol) and 4-bromobutyl phenylmethyl ether (0.04 mL, 0.21 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (4.5 mg, 7%). EI-MS m/z 442 (M+) Rt (2.01 min).

Provenance & Evidence