1-Bromo-4-(3-bromopropoxy)benzene → 4-[Hydroxy(diphenyl)methyl]-1-[3-(phenyloxy)propyl]-1-azoniabicyclo[2.2.1]heptane bromide

Participants

Reaction Steps

Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (31.5 mg, 0.113 mmol) and 4-bromophenyl 3-bromopropyl ether (46.1 mg, 0.157 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (35.7 mg, 55%). EI-MS m/z 492 (M+) Rt (1.94 min).

Provenance & Evidence