Benzene, (3-bromopropoxy)- → HCID 16042149, compound

Participants

Reaction Steps

Following the general procedure outlined in Example 24, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)acetonitrile (0.19 g, 0.658 mmol) and 3-bromopropyl phenyl ether (0.17 mL, 1.07 mmol) in 2CH3CN/3CHCl3 (15 mL) were reacted to give the desired product (0.146 g, 45%). EI-MS m/z 423 (M+), 1H NMR (400 MHz, CD3OD) δ 7.5 (m, 4H), δ 7.35 (m, 3H), δ 7.3-7.2 (m, 4H), δ 6.9 (m, 4H), δ 4.07 (m, 3H), 3.8-3.7 (m, 2H), δ 3.62 (m, 5H), δ 3.6-2.5 (m, 2H), δ 2.4-2.3 (m, 2H), δ 2.3-2.1 (m, 5H).

Provenance & Evidence