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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 499712Generated: October 29, 2026

Hydrochloric Acid → HCID 57421209, compound

https://huagongshe.com/reaction/499712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 12870394HCID 12870394—
SolventMethanolHCID 887—
ProductHCID 57421209HCID 57421209—

Reaction Conditions

Temperature60 °C

Reaction Steps

1.54 g of 2-imidazol-1-yl-2-methyl-propionic acid ethyl ester (73828-88-3) are dissolved in 20 ml of methanol. 20 ml of a 3M NaOH are added and the mixture is stirred for 16 hours at 60° C. The reaction mixture is then neutralised with 1M HCl and concentrated by evaporation. The title compound is identified from the residue by means of flash chromatography (SiO2 60 F) based on its Rf value.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07767690B2
Source datasetuspto-grants-2010_08
ORD IDord-a3a8ce8d435c4ebfaa72510060f1ee70
Source noteuspto-grants-2010_08