Ethyl isocyanate → N-ethyl-3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole-1-carboxamide

Participants

Reaction Steps

3-(2,6-Dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole was reacted with ethyl isocyanate in the same manner as in Example 17 to give a white solid of N-ethyl-3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole-1-carboxamide (5.37 g, yield: 62.8%). Melting point: 80˜82° C., 1H-NMR (Acetone-d6, Acetone, ppm): δ1.10 (t, J=7.2 Hz, 3H), 2.55 (d, J=0.8 Hz, 3H), 3.25 (dq, J=6.1 and 7.2 Hz, 2H), 5.71 (q, J=0.8 Hz, 1H), 7.37˜7.48 (brt, 1H, J=6.1 Hz), 7.67 (q, 2H, JHF=0.7 Hz).

Provenance & Evidence