HCID 12004033, compound → HCID 12004034, compound

Participants

Reaction Steps

The compound (180 mg) of Example 1 was dissolved in ethanol (7 ml), 10% palladium/carbon (50 mg) was added to the solution, and the mixture was hydrogenated at 25° C. The catalyst was removed by filtration from the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was purified by a silica gel chromatography (eluent: chloroform) to give 146 mg of the desired compound (cis:trans=1:4).

Provenance & Evidence