HCID 178491617, compound → HCID 178491618, compound

Participants

Reaction Steps

The compound (200 mg) of Example 14 was dissolved in ethanol (10 ml), 10% palladium/carbon (50 mg) was added to the mixture, and the mixture was hydrogenated at 25° C. The catalyst was removed by filtration from the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was purified by a silica gel chromatography (eluent: chloroform) to give 145 mg of the desired compound.

Provenance & Evidence