HCID 178491615, compound → HCID 178491616, compound

Participants

Reaction Steps

To a solution of the compound (315 mg) of Example 47 in ethanol (10 ml) was added platinum oxide (30 mg), and the mixture was hydrogenated at 25° C. The catalyst was removed by filtration from the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was purified by a silica gel chromatography (eluent: gradient from 100% hexane/0% ethyl acetate to 0% hexane/100% ethyl acetate) to give 275 mg of the desired compound.

Provenance & Evidence