Cyclobutanone → HCID 178491608, compound

HRID 500085Notes

Reaction equation

HRID 500085 reaction equation
C1(=O)CCC1.[CH2:6]([C:8]([CH2:29][CH3:30])=[CH:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([NH:16][C:17](=[O:28])[CH2:18][C:19]2[CH:24]=[CH:23][C:22]([OH:25])=[C:21]([O:26][CH3:27])[CH:20]=2)[CH2:12][CH2:11]1)C>>[C:8]1(=[CH:9][C@H:10]2[CH2:11][CH2:12][C@H:13]([NH:16][C:17](=[O:28])[CH2:18][C:19]3[CH:24]=[CH:23][C:22]([OH:25])=[C:21]([O:26][CH3:27])[CH:20]=3)[CH2:14][CH2:15]2)[CH2:29][CH2:30][CH2:6]1

Participants

3

Procedure

The above desired compound was prepared in a similar manner of Example 90 using cyclobutanone by which 3-pentanone of Example 90 (4) was replaced.

Sources & evidence

ORD record
ord-4b5f2700574d4659b16cc2ac3df6c6c8
Source dataset
uspto-grants-2010_08
Patent number
US07767854B2

Reaction notes

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