Acetic Anhydride → HCID 178425987, compound

HRID 500095Notes

Reaction equation

[C:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][N+:9]1[C:17]2[C:12](=[C:13]([F:21])[C:14]([F:20])=[C:15]([F:19])[C:16]=2[F:18])[C:11]([CH3:30])([CH2:22][CH2:23][CH2:24][CH2:25][S:26]([OH:29])(=[O:28])=[O:27])[CH:10]=1)([OH:3])=[O:2].Cl.C1(N=[CH:39][CH2:40][CH:41]=[N:42][C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)C=CC=CC=1.[C:49](OC(=O)C)(=O)C>C(O)(=O)C>[F:21][C:13]1[C:14]([F:20])=[C:15]([F:19])[C:16]([F:18])=[C:17]2[C:12]=1[C:11]([CH3:30])([CH2:22][CH2:23][CH2:24][CH2:25][S:26]([OH:29])(=[O:28])=[O:27])/[C:10](=[CH:49]\[CH:39]=[CH:40]\[CH:41]=[N:42]\[C:43]1[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=1)/[N:9]2[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:1]([OH:3])=[O:2]

Participants

Conditions

Temperature: 120 °C

Procedure

To 1-(5-carboxypentyl)-4,5,6,7-tetrafluoro-3-methyl-3-(4-sulfobutyl)-3H-indolium (12 mg) was added malonaldehyde bis(phenylimine) monohydrochloride (7 mg), acetic anhydride (2 ml) and acetic acid (1 ml). This mixture was heated to 120° C. for 1 hour 50 minutes after which time it was cooled to room temperature. This crude reaction mixture (ca. 5 mg/ml product) was used without purification as further described.

Workup

temperaturewas cooled to room temperature
customThis crude reaction mixture (ca. 5 mg/ml product)
customwas used without purification

Sources & evidence

ORD record: ord-6f4c87085d8d4ca6bd61374f85f818af
Source dataset: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07767829B2

Reaction notes

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