3-Methyl-2-butanone → HCID 87185964, compound

HRID 500098Notes

Reaction equation

HRID 500098 reaction equation
[F:1][C:2]1[C:7]2[C:8]([F:17])=[C:9]([NH:15][NH2:16])[C:10]([F:14])=[C:11]([F:13])[CH2:12][C:6]=2[C:5]([F:18])=[C:4]([F:19])[C:3]=1[F:20].[CH3:21][CH:22]([CH3:26])[C:23](=O)[CH3:24]>C(O)C>[F:1][C:2]1[C:7]2[C:8]([F:17])=[C:9]([NH:15][N:16]=[C:23]([CH:22]([CH3:26])[CH3:21])[CH3:24])[C:10]([F:14])=[C:11]([F:13])[CH2:12][C:6]=2[C:5]([F:18])=[C:4]([F:19])[C:3]=1[F:20]

Participants

4

Reactant 2

HCID 112513-Methyl-2-butanoneHCID 86646191HCID 86646191, compound

Product 1

HCID 87185964HCID 87185964, compoundYield 81.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To (1,2,3,4,6,7,9-heptafluoro-5H-benzo[7]annulen-8-yl)hydrazine (1 g) was added ethanol (20 ml) and 3-methyl-2-butanone (0.38 g). The mixture was heated to reflux for 3 hours after which time the volatiles were removed on a rotary evaporator to give a solid (1 g) which was used in the next step. M+=352

Workup

  1. temperatureThe mixture was heated
  2. temperatureto reflux for 3 hours after which time the volatiles
  3. customwere removed on a rotary evaporator

Sources & evidence

ORD record
ord-09dcc477c9f74383a29123bca34ec15d
Source dataset
uspto-grants-2010_08
Patent number
US07767829B2

Reaction notes

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