Acetic Anhydride → HCID 178425986, compound

HRID 500100Notes

Reaction equation

HRID 500100 reaction equation
[C:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][N+:9]1[C:17]2[C:12](=[C:13]([F:21])[C:14]([F:20])=[C:15]([F:19])[C:16]=2[F:18])[C:11]([CH3:30])([CH2:22][CH2:23][CH2:24][CH2:25][S:26]([OH:29])(=[O:28])=[O:27])[CH:10]=1)([OH:3])=[O:2].C(O[C:35](=O)[CH3:36])(=O)C>C(O)(=O)C>[F:21][C:13]1[C:14]([F:20])=[C:15]([F:19])[C:16]([F:18])=[C:17]2[C:12]=1[C:11]([CH3:30])([CH2:22][CH2:23][CH2:24][CH2:25][S:26]([OH:29])(=[O:28])=[O:27])/[C:10](=[CH:1]\[CH:4]=[CH:5]\[CH:6]=[CH:7]\[CH:8]=[N:9]\[C:35]1[CH:36]=[CH:13][CH:12]=[CH:11][CH:10]=1)/[N:9]2[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:1]([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 86646190HCID 86646190, compound

Product 1

HCID 178425986HCID 178425986, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
120 °C

Procedure

To 1-(5-carboxypentyl)-4,5,6,7-tetrafluoro-3-methyl-3-(4-sulfobutyl)-3H-indolium (24 mg) was added N-[5-(phenylamino)-2,4-pentadienylidene monohydrochloride (13 mg), acetic anhydride (4 ml) and acetic acid (2 ml). This mixture was heated to 120° C. for 1 hour 45 minutes after which time it was cooled to room temperature. This crude reaction mixture (ca. 5 mg/ml product) was used without purification as further described.

Workup

  1. temperaturewas cooled to room temperature
  2. customThis crude reaction mixture (ca. 5 mg/ml product)
  3. customwas used without purification

Sources & evidence

ORD record
ord-d76e5b6aa19f4ad18e9cdfe426c3c4de
Source dataset
uspto-grants-2010_08
Patent number
US07767829B2

Reaction notes

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