HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500165Generated: October 30, 2026
2-Fluoropyridine → HCID 67019304, compound
https://huagongshe.com/reaction/500165
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Fluoropyridine | HCID 9746 | — |
| Reactant | tert-butyl N-(pyrrolidin-3-yl)carbamate | HCID 2757234 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 67019304 | HCID 67019304 | 98.3% |
Reaction Steps
A mixture of 2-fluoropyridine (1.0 g, 10.3 mmol) and tert-butyl pyrrolidin-3-ylcarbamate (1.80 g, 9.66 mmol) was heated at 120° C. for 5 h. After cooling to RT, the solid formed was treated with ether, filtered, and washed with ether. The solid was collected and dried to give the desired product (2.50 g, 98.2%). LCMS: (M+H)=264.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07767675B2 |
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| Source dataset | uspto-grants-2010_08 |
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| ORD ID | ord-a0a1c508f1074507ae3331d763716c1e |
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| Source note | uspto-grants-2010_08 |
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