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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500207Generated: October 30, 2026

Methyl iodide → HCID 25145519, compound

https://huagongshe.com/reaction/500207

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 67224931HCID 67224931—
SolventDimethylformamideHCID 6228—
ProductHCID 25145519HCID 25145519—

Reaction Steps

To a solution of 6-{1-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidin-3-yl]cyclopropyl}quinoline (6 mg, 0.017 mmol) in N,N-dimethylformamide (200 μL) was added potassium carbonate (4.0 mg, 0.029 mmol) and methyl iodide (3 μL, 0.048 mmol). After stirring at RT for 16 h, the reaction mixture was purified by RP-HPLC to afford the desired product. LCMS: (M+H)=367.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07767675B2
Source datasetuspto-grants-2010_08
ORD IDord-e40421fc7c574df8baf65e14b1a4723a
Source noteuspto-grants-2010_08