HCID 67225166, compound → HCID 67223967, compound

HRID 500209Notes

Reaction equation

HRID 500209 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([NH2:14])=[N:10][CH:9]=2)=[CH:4][CH:3]=1.Cl[CH:16]([C:19]1([C:22]2[CH:23]=[C:24]3[C:29](=[CH:30][CH:31]=2)[N:28]=[CH:27][CH:26]=[CH:25]3)[CH2:21][CH2:20]1)[CH:17]=O>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[N:10][C:11]3[N:12]([C:16]([C:19]4([C:22]5[CH:23]=[C:24]6[C:29](=[CH:30][CH:31]=5)[N:28]=[CH:27][CH:26]=[CH:25]6)[CH2:21][CH2:20]4)=[CH:17][N:14]=3)[N:13]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 67225166HCID 67225166, compoundHCID 86621504Chloro(1-quinolin-6-ylcyclopropyl)acetaldehyde

Product 1

HCID 67223967HCID 67223967, compound

Procedure

This compound was prepared from the condensation of 6-(4-bromophenyl)-1,2,4-triazin-3-amine and chloro(1-quinolin-6-ylcyclopropyl)acetaldehyde using a procedure analogous to that described for the synthesis of Example 7, Step 8. LCMS: (M+H)=442.3/444.2.

Workup

  1. customthat described for the synthesis of Example 7, Step 8

Sources & evidence

ORD record
ord-709aa247520e4fb5bda5c677ec48d92d
Source dataset
uspto-grants-2010_08
Patent number
US07767675B2

Reaction notes

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