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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500240Generated: October 30, 2026

Trifluoroacetic acid → HCID 67224038, compound

https://huagongshe.com/reaction/500240

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67224311HCID 67224311—
SolventDichloromethaneHCID 6344—
ProductHCID 67224038HCID 67224038—

Reaction Steps

Trifluoroacetic Acid (0.5 mL) was added to a solution of tert-butyl 4-{4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-1H-pyrazol-1-yl}piperidine-1-carboxylate (0.014 g, 0.027 mmol) in methylene chloride (0.5 mL) and stirred at RT for 1 h. The volatiles were removed under reduced pressure and the residue was purified by RP-HPLC (pH 10) to give the desired product. LCMS: (M+H)=411.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07767675B2
Source datasetuspto-grants-2010_08
ORD IDord-401962e9f888412da609c2b19b2ae9cb
Source noteuspto-grants-2010_08