Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500482Generated: October 29, 2026

(+)-Epichlorohydrin → tert-Butyl (2S)-2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate

https://huagongshe.com/reaction/500482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+)-EpichlorohydrinHCID 149428—
ReactantTert-butyl 2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylateHCID 21867670—
Producttert-Butyl (2S)-2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylateHCID 86588968—

Reaction Steps

The sub-title compound was prepared according to the procedures described in steps (i) to (v) above for the synthesis of tert-butyl 2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate, but using (S)-(+)-epichlorohydrin in place of epichlorohydrin in step (i).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772229B2
Source datasetuspto-grants-2010_08
ORD IDord-34bfae349a2b4a85b2f5c6aed1709d01
Source noteuspto-grants-2010_08