HCID 86604167, compound → HCID 86604169, compound

HRID 500810Notes

Reaction equation

HRID 500810 reaction equation
[ClH:1].[F:2][C:3]1[CH:4]=[C:5]([NH:27][C:28]([NH:30][C:31](=[O:39])[CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[S:29])[CH:6]=[CH:7][C:8]=1[O:9][C:10]1[CH:15]=[CH:14][N:13]=[C:12]2[CH:16]=[C:17]([C:19]([N:21]3[CH2:26][CH2:25][CH2:24][CH2:23]C3)=[O:20])[S:18][C:11]=12.FC1C=C(NC(NC(=O)CC2C=CC=CC=2)=S)C=CC=1OC1C=CN=C2C=C(C(N3CCCCC3)=O)SC=12>>[ClH:1].[F:2][C:3]1[CH:4]=[C:5]([NH:27][C:28]([NH:30][C:31](=[O:39])[CH2:32][C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)=[S:29])[CH:6]=[CH:7][C:8]=1[O:9][C:10]1[CH:15]=[CH:14][N:13]=[C:12]2[CH:16]=[C:17]([C:19]([N:21]3[CH2:23][CH2:24][CH2:25][CH2:26]3)=[O:20])[S:18][C:11]=12

Participants

3

Reactant 2

HCID 86604167HCID 86604167, compoundHCID 86604168HCID 86604168, compound

Product 1

HCID 86604169HCID 86604169, compound

Procedure

Following the procedure described above for the synthesis of compound 136a (example 93) but substituting compound 135d (example 92, table 11) for the compound 8o (example 37, table 6), title compound 136b was obtained. Characterization of this material is provided in Table 12.

Sources & evidence

ORD record
ord-ecdfebac4b794a65baf71873bad2face
Source dataset
uspto-grants-2010_08
Patent number
US07772247B2

Reaction notes

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