Dimethylamine → (7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone

Participants

Role	Name	HCID	Charge
Reactant	Dimethylamine	HCID 674	—
Reactant	Pyrrolidine	HCID 31268	—
Reactant	7-Chloro-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide	HCID 22143537	—
Product	(7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone	HCID 11173165	—

Reaction Steps

Following the procedures described above for the synthesis of compound 5 (scheme 1, example 1) but replacing dimethyl amine in the step 4 for pyrrolidine, title compound 139 was obtained. LRMS (M+1) 267.1 (100%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07772247B2
Source dataset	uspto-grants-2010_08
ORD ID	ord-be6a7d91d8b44742b1652ba84dfd3ae0
Source note	uspto-grants-2010_08