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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500818Generated: October 27, 2026

4-(4-BOC-Piperazino)phenylboronic acid → HCID 59424537, compound

https://huagongshe.com/reaction/500818

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-BOC-Piperazino)phenylboronic acidHCID 5233014—
Reactant7-(2-Fluoro-4-nitrophenoxy)-2-(4-(methylsulfonyl)phenyl)thieno[3,2-b]pyridineHCID 58772878—
ProductHCID 59424537HCID 5942453770%

Reaction Steps

Starting from the nitro-bromo compound 42, following the procedure described above for the synthesis of compound 48 (scheme 10, example 55) but substituting 4,4,5,5-tetramethyl-2-(4-(methylsulfonyl)phenyl)-1,3,2-dioxaborolane for 4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylboronic acid, title compound 156 was obtained in 70% yield. LRMS (M+1) 550.6 (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772247B2
Source datasetuspto-grants-2010_08
ORD IDord-0fed0d1d813642eca888087952f1f1e4
Source noteuspto-grants-2010_08