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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500844Generated: October 31, 2026

4-(7-(4-Nitrophenoxy)thieno[3,2-b]pyridin-2-yl)phenol → 4-(7-(4-Aminophenoxy)thieno[3,2-b]pyridin-2-yl)phenol

https://huagongshe.com/reaction/500844

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(7-(4-Nitrophenoxy)thieno[3,2-b]pyridin-2-yl)phenolHCID 136059646—
Reactant4-(7-(4-Amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)phenolHCID 136059647—
Product4-(7-(4-Aminophenoxy)thieno[3,2-b]pyridin-2-yl)phenolHCID 13605965183%

Reaction Steps

Starting from the compound 198 and following the procedure described above for the synthesis of compound 154 (scheme 28), title compound 199 was obtained in 83% yield. LRMS (M+1) 335.0 (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772247B2
Source datasetuspto-grants-2010_08
ORD IDord-abc27621febd43c58058366ed45cdb65
Source noteuspto-grants-2010_08