7-chloro-2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridine → 7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	7-chloro-2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridine	HCID 22143563	—
Reactant	7-(2-Fluoro-4-nitrophenoxy)-2-(thiazol-2-yl)thieno[3,2-b]pyridine	HCID 59424425	—
Product	7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine	HCID 59424518	45%

Reaction Steps

Starting from compound 214 (scheme 46) and following the procedure described above for the synthesis of compound 11 (scheme 2, step 3, example 12), title compound 218 was obtained in 45% yield. MS (m/z) 371.1 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07772247B2
Source dataset	uspto-grants-2010_08
ORD ID	ord-cf794f14ca8a4ed7a1b3dc2874c6a5f3
Source note	uspto-grants-2010_08