4-Methylpyrazole → N-(4-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

Participants

Role	Name	HCID	Charge
Reactant	4-Methylpyrazole	HCID 3406	—
Reactant	3,5-Dimethylpyrazole	HCID 6210	—
Reactant	N-(4-(2-(4-Methyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide	HCID 86604190	—
Product	N-(4-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide	HCID 86604192	—

Reaction Steps

Following the procedures described above for the synthesis of compound 258a (example 215, scheme 58) but replacing 4-methyl-1H-pyrazole in the step 1 with 3,5-dimethyl-1H-pyrazole, title compound 258c was obtained. Characterization of 258c is provided in the table 23.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07772247B2
Source dataset	uspto-grants-2010_08
ORD ID	ord-2ea772a746b4439d86c316a6c9710199
Source note	uspto-grants-2010_08