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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500898Generated: October 31, 2026

7-(2-fluoro-4-nitrophenoxy)-1H-pyrrolo[2,3-c]pyridine → 6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

https://huagongshe.com/reaction/500898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(2-fluoro-4-nitrophenoxy)-1H-pyrrolo[2,3-c]pyridineHCID 59424641—
Reactant6-Bromo-7-chlorothieno(3,2-b)pyridineHCID 59424655—
Product6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 5942445761%

Reaction Steps

Starting from the compound 271 and following the procedure described above for the synthesis of compound 260 (scheme 59, example 218, step 2), title compound 272 was obtained in 61% yield as an off-white solid. MS (m/z): 368.9(M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772247B2
Source datasetuspto-grants-2010_08
ORD IDord-f869cb4a864344f38124fd6ca783f4b3
Source noteuspto-grants-2010_08