HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine → 4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine | HCID 59424457 | — |
| Reactant | 4-(1H-Pyrrolo[2,3-c]pyridin-7-yloxy)-3-fluorobenzenamine | HCID 59424629 | — |
| Product | 4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine | HCID 59424676 | 92% |
Reaction Steps
Starting from the compound 272 and following the procedure described above for the synthesis of compound 261 (scheme 59, example 218, step 3), title compound 273 was obtained in 92% yield as a light brown solid. MS (m/z): 340.0(M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772247B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-47feed4ed13a465cbf1edd5f0ea9b032 |
| Source note | uspto-grants-2010_08 |