HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-Piperidin-4-yl-7,9-dihydro-8H-purin-8-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 7-(1-benzylpiperidin-4-yl)-7,9-dihydro-8H-purin-8-one | HCID 22293261 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 7-Piperidin-4-yl-7,9-dihydro-8H-purin-8-one hydrochloride | HCID 22293197 | — |
Reaction Steps
A mixture of 7-(1-benzylpiperidin-4-yl)-7,9-dihydro-8H-purin-8-one (1.2 g, 3.7 mmol) in 4N hydrogen chloride in dioxane (50 mL), was stirred vigorously at room temperature for 3 h. The reaction was concentrated in vacuo to give the title compound as a white solid. MS 220 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772224B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-64f2a940c21d4fcc8cd8dca1a6d01e29 |
| Source note | uspto-grants-2010_08 |