Ammonia → N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)acetamide

HRID 501238Notes

Reaction equation

[C:1]([NH:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([S:14](Cl)(=[O:16])=[O:15])[CH:11]=2)[CH2:6]1)(=[O:3])[CH3:2].[NH3:18]>>[S:14]([C:10]1[CH:11]=[C:12]2[C:7](=[CH:8][CH:9]=1)[CH2:6][CH:5]([NH:4][C:1](=[O:3])[CH3:2])[CH2:13]2)(=[O:16])(=[O:15])[NH2:18]

Participants

Reactant 2

HCID 222Ammonia

HCID 203478562-Acetamido-2,3-dihydro-1h-indene-5-sulfonyl chloride

Product 1

HCID 11414131N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)acetamide

Procedure

was prepared from 2-Acetylamino-indan-5-sulfonyl chloride and an excess of ammonia.

Sources & evidence

ORD record: ord-e1bc90b0faee462ab8eb219fe4bbc341
Source dataset: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07772257B2

Reaction notes

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