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1-(3-Chlorophenyl)piperazine monohydrochloride → HCID 178455803、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3-Chlorophenyl)piperazine monohydrochloride | HCID 25681 | — |
| 反応物 | 1-(4-Trifluoromethylphenyl)piperazine hydrochloride | HCID 23112422 | — |
| 反応物 | HCID 178455808 | HCID 178455808 | — |
| 反応物 | HCID 178505300 | HCID 178505300 | — |
| 生成物 | HCID 178455803 | HCID 178455803 | — |
反応手順
Follow the procedure of Example 11e, and substitute methane sulfonic acid 2-(trans-4-ethyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester (Example 13d) for methane sulfonic acid 2-(trans-4-methyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester and 4-(4-trifluoromethyl-phenyl)-piperazine hydrochloride for 1-(3-chloro-phenyl)-piperazine hydrochloride therein to obtain the title compound MS m/z=438 (M+H)+, 78.5% pure by HPLC assay.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07772252B2 |
| 出典データセット | uspto-grants-2010_08 |
| ORD ID | ord-8ecf6db86a98491a827852d189b96235 |
| 出典メモ | uspto-grants-2010_08 |