HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 501301Generated: October 30, 2026
4-[1-(3-Bromo-5-methyl-thiophen-2-yl)-methanoyl]-piperidine-1-carboxylic acid tert-butyl ester → 4-[1-(3-Bromo-5-methyl-thiophen-2-yl)-1-hydroxyimino-methyl]-piperidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/501301
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-[1-(3-Bromo-5-methyl-thiophen-2-yl)-methanoyl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 58817682 | — |
| Reactant | 4-[1-(3-bromo-4-methyl-thiophen-2-yl)-1-hydroxyimino-methyl]-piperidine-1-carboxylic Acid tert-butyl Ester | HCID 72434573 | — |
| Product | 4-[1-(3-Bromo-5-methyl-thiophen-2-yl)-1-hydroxyimino-methyl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 72434560 | — |
Reaction Steps
Prepared essentially as 29b except that 4-[1-(3-Bromo-5-methyl-thiophen-2-yl)-methanoyl]-piperidine-1-carboxylic acid tert-butyl ester is used as the starting material and the reaction mixture was stirred at 70° C. for 6 hours. LC/MS (ESI), m/e 347 (M-56) and 403 (MH+), retention time 2.03 minutes. Condition II.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07772252B2 |
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| Source dataset | uspto-grants-2010_08 |
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| ORD ID | ord-77f7d9a2ea7741eaba229571dbbe3016 |
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| Source note | uspto-grants-2010_08 |
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