HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-1-(2-cyanobenzyl)-6-oxo-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride → 8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-1-(2-cyanobenzyl)-6-oxo-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride | HCID 23070665 | — |
| Reactant | t-butyl [1-[7-(2-butynyl)-2-chloro-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purin-8-yl]piperidin-3-yl]carbamate | HCID 57472739 | — |
| Product | 8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride | HCID 23070888 | — |
Reaction Steps
The title compound was synthesized by using t-butyl [1-[7-(2-butynyl)-2-chloro-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purin-8-yl]piperidin-3-yl]carbamate according to the method described in Example 242 (f) and (g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772226B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-cdae4583e2794eb792e7edc47264497b |
| Source note | uspto-grants-2010_08 |