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HRID501503

反应详情

EQUATION

反应方程式

HRID 501503 的结构方程式

REACTANTS

反应物

2
结构：[Cl-].[Cl-].[Zn+2]
HCID3007855

Zinc chloride

Cl2Zn

结构：CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)[O-])[C@H]21.[Na+]
HCID16759173

Pravastatin sodium

C23H35NaO7

PRODUCTS

生成物

1
结构：CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@H]21.[Zn]
HCID86603140

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

2 次

PROCEDURE

实验过程

2 equivalents of pravastatin sodium dissolved in de-ionized water are reacted with a solution having 1 equivalent of zinc chloride in de-ionized water. Precipitation of crystalline pravastatin zinc occurs immediately at room temperature. The resultant salt was a 2:1 pravastatin to zinc salt. The preparation and characterization of pravastatin zinc are described more completely in Example 7 of US Application No. 20060034815.

WORKUP

后处理

  1. customare reacted with a solution
  2. customPrecipitation of crystalline pravastatin zinc
  3. customoccurs immediately at room temperature
  4. customThe preparation and characterization of pravastatin zinc