1-Acetamido-5,6,7,8-tetrahydronaphthalene → 7-Amino-3-methyl-3H-benzimidazole-4-carbonitrile

HRID 501529Notes

Reaction equation

HRID 501529 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[C:10]([NH2:11])[C:5]=2[N:4]=[CH:3]1.[C:12]1([NH:22]C(=O)C)C2CCCCC=2C=CC=1.Cl.NC1C2CCCCC=2C(C#N)=CC=1>>[NH2:11][C:10]1[C:5]2[N:4]=[CH:3][N:2]([CH3:1])[C:6]=2[C:7]([C:12]#[N:22])=[CH:8][CH:9]=1

Participants

4

Reactant 3

HCID 2320651-Acetamido-5,6,7,8-tetrahydronaphthaleneHCID 15019774-Amino-1-methylbenzimidazoleHCID 1317269774-Amino-5,6,7,8-tetrahydronaphthalene-1-carbonitrile, hydrochloride salt

Product 1

HCID 597542827-Amino-3-methyl-3H-benzimidazole-4-carbonitrile

Procedure

The title compound was prepared from compound 9A by procedures analogous to those described in Experiment 2 (2A to 2D).

Sources & evidence

ORD record
ord-67f38ca010774ad1b730c7eeaeae5bdb
Source dataset
uspto-grants-2010_08
Patent number
US07772267B2

Reaction notes

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