5-Amino-2,2-dimethyl-2H-chromene-8-carbonitrile → 2-(Allyloxy)-4-aminobenzonitrile

HRID 501531Notes

Reaction equation

HRID 501531 reaction equation
[CH2:1]([O:4][C:5]1[CH:12]=[C:11]([N+:13]([O-])=O)[CH:10]=[CH:9][C:6]=1[C:7]#[N:8])[CH:2]=[CH2:3].NC1C=CC(C#N)=C2C=1C=CC(C)(C)O2>>[CH2:1]([O:4][C:5]1[CH:12]=[C:11]([NH2:13])[CH:10]=[CH:9][C:6]=1[C:7]#[N:8])[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 597542965-Amino-2,2-dimethyl-2H-chromene-8-carbonitrileHCID 597543072-(Allyloxy)-4-nitrobenzonitrile

Product 1

HCID 597542362-(Allyloxy)-4-aminobenzonitrileYield 97.6%

Procedure

The title compound (1.70 g) as a light yellow solid was prepared from compound 10A (2.04 g, 10 mmol) by procedures analogous to those described in Experiment 6C.

Sources & evidence

ORD record
ord-0b864ed1dbe6463eaaa12067b365154f
Source dataset
uspto-grants-2010_08
Patent number
US07772267B2

Reaction notes

Loading…