2-Quinolinecarbonitrile,6-amino-(9CI) → 6-Amino-N-benzyl-2-quinolone

HRID 501580Notes

Reaction equation

HRID 501580 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9](=[O:21])[CH:8]=[CH:7]2)([O-])=O.C(C1C=CC2C(=CC=C(N)C=2)N=1)#N>>[NH2:1][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[C:9](=[O:21])[CH:8]=[CH:7]2

Participants

3

Reactant 2

HCID 451170492-Quinolinecarbonitrile,6-amino-(9CI)HCID 59754358HCID 59754358, compound

Product 1

HCID 597542136-Amino-N-benzyl-2-quinolone

Procedure

The title compound (34 mg) was prepared from compound 46C in a manner similar to that described in Experiment 45C. LC/MS m/z 251 [M+H]+.

Sources & evidence

ORD record
ord-568d6347d86e48c98a8f0df4d90c1ed7
Source dataset
uspto-grants-2010_08
Patent number
US07772267B2

Reaction notes

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