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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50161Generated: October 29, 2026

6-Bromo-4-(3-chlorophenyl)-2-methoxyquinoline → HCID 22465433, compound

https://huagongshe.com/reaction/50161

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-4-(3-chlorophenyl)-2-methoxyquinolineHCID 12016672—
Reactant(3-Chloro-thiophen-2-yl)-(3-methyl-3h-imidazol-4-yl)-methanoneHCID 22465392—
ProductHCID 22465433HCID 2246543351.2%

Reaction Steps

Following the same procedure as described in example 1E, 6-bromo-4-(3-chloro-phenyl)-2-methoxy-quinoline (300 mg, 0.859 mmol) and (3-chloro-thiophen-2-yl)-(3-methyl-3H-imidazol-4-yl)-methanone (230 mg 1.032 mmol) generated the title compound of 21A as a yellow solid (218.5 mg, 51% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710209B2
Source datasetuspto-grants-2004_03
ORD IDord-5fce0d5f8b5f44c08684cb5ffb994dc0
Source noteuspto-grants-2004_03