Sodium Thiosulfate → HCID 59754351, compound

Participants

Reaction Steps

To 66E (100 mg, 0.279 mmol) in CH2Cl2 was added Dess-Martin periodinane (236 mg, 0.556 mmol) and the reaction was stirred at rt overnight. Saturated aqueous Na2S2O3 and NaHCO3 were added and the whole was stirred vigorously for 0.5 h. The layers were separated, the organic layer was washed with a mixture of saturated aqueous Na2S2O3 and NaHCO3 followed by brine, dried (MgSO4), and was then filtered and concentrated to obtain the title compound (96.0 mg) as a white film.

Provenance & Evidence