Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 501634Generated: October 26, 2026

4-Amino-2-fluoro-3-methylbenzonitrile → 2-Fluoro-4-isocyanato-3-methylbenzonitrile

https://huagongshe.com/reaction/501634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-fluoro-3-methylbenzonitrileHCID 45078676—
Reactant4-Isocyanato-5,6,7,8-tetrahydronaphthalene-1-carbonitrileHCID 59754304—
Product2-Fluoro-4-isocyanato-3-methylbenzonitrileHCID 59754317—

Reaction Steps

2-Fluoro-4-isocyanato-3-methylbenzonitrile was prepared from 4-amino-2-fluoro-3-methyl-benzonitrile (72D) following a procedure analogous to the procedure used in the preparation of compound 2E (Example 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772267B2
Source datasetuspto-grants-2010_08
ORD IDord-a0c1ce91d8cf47bd98535fea19c46ae1
Source noteuspto-grants-2010_08