HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-trifluoro-N-((1S,3R)-3-hydroxy-6-isopropoxy-2,3-dihydro-1H-inden-1-yl)acetamide → 3-(Allyloxy)-6-phenoxy-2,3-dihydro-1H-inden-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-trifluoro-N-((1S,3R)-3-hydroxy-6-isopropoxy-2,3-dihydro-1H-inden-1-yl)acetamide | HCID 59423688 | — |
| Reactant | (1S,3R)-3-(Allyloxy)-6-propoxy-2,3-dihydro-1H-inden-1-amine | HCID 59423826 | — |
| Product | 3-(Allyloxy)-6-phenoxy-2,3-dihydro-1H-inden-1-amine | HCID 59423743 | — |
Reaction Steps
Step BB (1). 3-(Allyloxy)-6-phenoxy-2,3-dihydro-1H-inden-1-amine was prepared using a series of procedures analogous to Steps AU (1-5), X (1) and U (2). 1H NMR (300 MHz, CDCl3) δ 1.6-1.8 (m, 1H) 2.7-2.9 (m, 1H) 4.0-4.2 (m, 3H) 4.7-4.8 (t, 1H) 5.1-5.4 (m, 2H) 5.8-6.0 (m, 1H) 6.8-7.1 (m, 5H) 7.2-7.4 (m, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772221B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-305b3c0772984a2ab4d076816c7948eb |
| Source note | uspto-grants-2010_08 |